منابع مشابه
Quantitative sodium MRI of the mouse prostate.
A method was developed for quantitative sodium MRI of the mouse prostate at 9.4 T. A small loop-gap radiofrequency coil was constructed and dual-tuned to both the proton and sodium frequencies. The location and boundary of the mouse prostate were localized using high-resolution T(2)-weighted proton images, and sodium images were acquired with 1mm isotropic resolution using a short echo time (0....
متن کاملSodium MRI of Intervertebral Disc Degeneration
Objective: To establish sodium MRI as a non-invasive method for measuring intervertebral disc proteoglycan content Introduction: Intervertebral disc (IVD) degeneration is a common and sometimes debilitating condition, incurring tremendous financial cost on society. The initial stage of IVD degeneration involves the breakdown of proteoglycans (PG) in the nucleus pulposus (NP) region of the disc[...
متن کاملSodium (23Na) MRI detects elevated muscular sodium concentration in Duchenne muscular dystrophy.
OBJECTIVE In boys with Duchenne muscular dystrophy (DMD), (1)H MRI suggested muscular edema before fatty degeneration. Using specific (23)Na MRI sequences, we tested the hypothesis that the edema is caused by an osmotic effect due to increased myoplasmic Na(+) content rather than inflammation that would lead to extracellular edema. METHODS Eleven patients with DMD (mean age, 10 ± 5 years) and...
متن کاملRepeatability and age-related change of sodium in the knee articular cartilage measured with sodium MRI
Introduction Aging is one of the leading risk factors for osteoarthritis [1]. Proteoglycan, one of the major components of articular cartilage, undergoes loss and structural changes with aging [2]. Proteoglycan has a negative fixed charge density, which is balanced by positively charged sodium in the cartilage. Imaging of cartilage sodium is a potential tool to evaluate spatial proteoglycan con...
متن کاملWhat can sodium MRI reveal about sodium accumulation in the brain: implications for multiple sclerosis
Multiple sclerosis: needs for biomarkers of neuronal injury Multiple sclerosis (MS) is a chronic disease of the CNS, representing the leading cause of neuro logical disability in young adults. Focal inflam matory and demyelinating lesions disseminated in the cerebral white matter have been considered for several decades to be the main feature of MS. However, recent histological studies have a...
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ژورنال
عنوان ژورنال: Current Opinion in Nephrology and Hypertension
سال: 2017
ISSN: 1062-4821
DOI: 10.1097/mnh.0000000000000370